Urocanic acid( 4-Imidazoleacrylic acid )

Catalog No. M19542 CAS No. 104-98-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Urocanic acid
Note

Research use only, not for human use.
Brief Description

Urocanic acid produced in the upper layers of mammalian skin is a major absorber of ultraviolet radiation.
Description

Urocanic acid produced in the upper layers of mammalian skin is a major absorber of ultraviolet radiation.(In Vitro):Urocanic acid (UCA) is formed in the upper layers of the epidermis where filaggrin, a histidine-rich filamentous protein produced after caspase-14 cleavage of profilaggrin, is broken down by proteinases into component amino acids.
In Vitro

Urocanic acid (UCA) is formed in the upper layers of the epidermis where filaggrin, a histidine-rich filamentous protein produced after caspase-14 cleavage of profilaggrin, is broken down by proteinases into component amino acids.
In Vivo

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Synonyms

4-Imidazoleacrylic acid
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Inflammation/Immunology
Indication

Dry eyes

1.Gibbs NK et al. Recent advances in urocanic acid photochemistry photobiology and photoimmunology. Photochem Photobiol Sci. 2008 Jun;7(6):655-67.

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